The main focus of my research is the application of quantitative MRI techniques in neurological disorders in order to improve diagnosis, better understand the disease, and develop measureable biomarkers to track treatment success. During my MSc and PhD I specialised in multiple sclerosis and I am now starting to apply the same technqiues in anti-NMDA encephalitis during my post-doc.

As a translational neuroscientist, I primarily find interesting technological developments from the MRI community and translate these into the clinic by testing and applying them in neurological disorders. I also work with animal models, which enables us to answer questions about the disease that require more invasive methods, such as histology, and translate the findings from these experiments back to the disease in humans.

My main expertise is in MRI analysis but I get to dip my toes in a wide range of techniques and approaches. This means that I have the opportunity to work and collaborate with a wide range of experts in different fields, utilising my organisational, project management and networking skills, which I love!

The key methods I use in my research are:

  • Programming for MRI analysis (Python, MATLAB, Bash, FSL, ANTX, SPM12, CAT12)
  • Programming for statistical analysis and presentations (R, Python)
  • Neuropsychological assessment
  • MRI acquisition in humans, human tissue, and small animals
  • Histology and immunohistochemistry
  • Analysis of clinical data (diagnostic information including lumbar puncture, cognitive and questionnaire data)

The main MRI techniques I use are:

  • Quantitative Multi-Parametric Mapping (MPM)
  • T1w/T2w Ratio

Education

PhD Fellow: October 2017 - Present

International Graduate School Medical Neurosciences, Humboldt University of Berlin, Germany

Funded by the Einstein Center for Neurosciences, Berlin, Germany

MSc Human Cognitive Neuropsychology (Distinction): October 2016 - September 2017

University of Edinburgh, Edinburgh, Scotland

BSc (Hons) Psychology (First Class): October 2012 - June 2016

University of Bath, Bath, England


Conferences

2019:

  • European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Stockholm, Sweden
    • Poster presentation entitled “Association between humoral cerebrospinal fluid markers, periventricular lesion density and cortical thickness in early multiple sclerosis”
  • Fondation pour l’aide á la recherche sur la sclerose en placques (ARSEP), Paris, France
    • Poster presentation entitled “Standardization of T1w/T2w Ratio Improves Detection of Tissue Damage in MS”
  • International Multiple Sclerosis Cognition Society (IMSCOGS), Amsterdam, Netherlands
  • Small Animal MRI Symposium (SAMS), Hannover, Germany
    • Poster presentation entitled “A study protocol to assess the validity and translational potential of multi-parameteric mapping of R1, R2*, PD and MT”

2018:

  • European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Berlin, Germany
    • Poster presentation entitled “Normal Appearing White Matter Damage Detected by the Standardized T1w/T2w Ratio”
  • International Multiple Sclerosis Cognition Society (IMSCOGS), Berlin, Germany
    • Assisted with running of the conference

Invited Talks

2019:

  • Neuroimmunological Colloquium Neuroimmunological Colloquium, Charité - Universitätsmedizin Berlin, Berlin, Germany
    • talk entitled “Detecting normal appearing white matter damage in MS using clinical MRI”
  • Workshop der Differentialdiagnosen der MS (MS Differential Diagnosis Workshop), Graz, Austria
    • Merck funded talk entitled “Assessing cognitive function of all MS patients at time of first diagnosis” (in German)